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Inhibition of Klebsiella β-Lactamases (SHV-1 and KPC-2) by Avibactam: A Structural Study

β-Lactamase inhibition is an important clinical strategy in overcoming β-lactamase-mediated resistance to β-lactam antibiotics in Gram negative bacteria. A new β-lactamase inhibitor, avibactam, is entering the clinical arena and promising to be a major step forward in our antibiotic armamentarium. A...

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Detalles Bibliográficos
Autores principales:	Krishnan, Nikhil P., Nguyen, Nhu Q., Papp-Wallace, Krisztina M., Bonomo, Robert A., van den Akker, Focco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560403/ https://www.ncbi.nlm.nih.gov/pubmed/26340563 http://dx.doi.org/10.1371/journal.pone.0136813

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