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Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate

We recently described a new, live-attenuated vaccine candidate for chikungunya (CHIK) fever, CHIKV/IRES. This vaccine was shown to be well attenuated, immunogenic and efficacious in protecting against CHIK virus (CHIKV) challenge of mice and nonhuman primates. To further evaluate its preclinical saf...

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Detalles Bibliográficos
Autores principales:	Plante, Kenneth S, Rossi, Shannan L., Bergren, Nicholas A., Seymour, Robert L., Weaver, Scott C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560411/ https://www.ncbi.nlm.nih.gov/pubmed/26340754 http://dx.doi.org/10.1371/journal.pntd.0004007

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