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Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor

The α7nicotinic receptor (nAChR) is a major subtype of the nAChRs in the central nervous system, and the receptor plays an important role in brain function. In the dbSNP database, there are 55 single nucleotide polymorphisms (SNPs) that cause missense mutations of the human α7nAChR in the coding reg...

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Detalles Bibliográficos
Autores principales: Zhang, Qinhui, Du, Yingjie, Zhang, Jianliang, Xu, Xiaojun, Xue, Fenqin, Guo, Cong, Huang, Yao, Lukas, Ronald J., Chang, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560414/
https://www.ncbi.nlm.nih.gov/pubmed/26340537
http://dx.doi.org/10.1371/journal.pone.0137588