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Regulatory Divergence of Transcript Isoforms in a Mammalian Model System

Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk gene expression levels and gene-internal splicing. U...

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Detalles Bibliográficos
Autores principales: Leigh-Brown, Sarah, Goncalves, Angela, Thybert, David, Stefflova, Klara, Watt, Stephen, Flicek, Paul, Brazma, Alvis, Marioni, John C., Odom, Duncan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560434/
https://www.ncbi.nlm.nih.gov/pubmed/26339903
http://dx.doi.org/10.1371/journal.pone.0137367