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Regulatory Divergence of Transcript Isoforms in a Mammalian Model System
Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk gene expression levels and gene-internal splicing. U...
Autores principales: | Leigh-Brown, Sarah, Goncalves, Angela, Thybert, David, Stefflova, Klara, Watt, Stephen, Flicek, Paul, Brazma, Alvis, Marioni, John C., Odom, Duncan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560434/ https://www.ncbi.nlm.nih.gov/pubmed/26339903 http://dx.doi.org/10.1371/journal.pone.0137367 |
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