Cargando…

Combined 2-deoxy glucose and metformin improves therapeutic efficacy of sodium-iodide symporter-mediated targeted radioiodine therapy in breast cancer cells

Radiosensitization using either metformin or 2-deoxy-d-glucose (2-DG) in various cancer cells has been reported. The present study reveals novel information on combining these drugs to enhance radiosensitization effect in breast cancer (BC) cells. Responses to low-dose Cobalt60 radiation, as well as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chatterjee, Sushmita, Thaker, Nirmal, De, Abhijit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560438/ https://www.ncbi.nlm.nih.gov/pubmed/26355636 http://dx.doi.org/10.2147/BCTT.S84648

Ejemplares similares

Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake
por: Chung, Taemoon, et al.
Publicado: (2015)

Dimerization of the Sodium/Iodide Symporter
por: Thompson, Rebecca J., et al.
Publicado: (2019)

Targeting of tumor radioiodine therapy by expression of the sodium iodide symporter under control of the survivin promoter
por: Huang, R, et al.
Publicado: (2011)

Induction of Sodium/Iodide Symporter (NIS) Expression and Radioiodine Uptake in Non-Thyroid Cancer Cells
por: Liu, Zhi, et al.
Publicado: (2012)

Extracellular vesicles deliver sodium iodide symporter protein and promote cancer cell radioiodine therapy
por: Lee, Jin Hee, et al.
Publicado: (2022)

Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine
por: Hutzen, Brian, et al.
Publicado: (2012)

Quantitative Immunohistochemical Analysis Reveals Association between Sodium Iodide Symporter and Estrogen Receptor Expression in Breast Cancer
por: Chatterjee, Sushmita, et al.
Publicado: (2013)

The glial fibrillary acidic protein promoter directs sodium/iodide symporter gene expression for radioiodine therapy of malignant glioma
por: LI, WEI, et al.
Publicado: (2013)

Enhancement of Natural Killer Cell Cytotoxicity by Sodium/Iodide Symporter Gene-Mediated Radioiodine Pretreatment in Breast Cancer Cells
por: Kim, Hae Won, et al.
Publicado: (2013)

A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer
por: Trujillo, Miguel A., et al.
Publicado: (2012)

Sodium iodide symporter-targeted gene therapy in glioblastoma
por: Nicola, Juan Pablo, et al.
Publicado: (2023)

Autophagy activity is associated with membranous sodium iodide symporter expression and clinical response to radioiodine therapy in non-medullary thyroid cancer
por: Plantinga, Theo S., et al.
Publicado: (2016)

The Association Between Radioiodine Refractory in Papillary Thyroid Carcinoma, Sodium/Iodide Symporter Expression, and BRAF(V600E) Mutation
por: Anekpuritanang, Tauangtham, et al.
Publicado: (2021)

Tumor microenvironment affects exogenous sodium/iodide symporter expression
por: Castillo-Rivera, Fabio, et al.
Publicado: (2020)

Radioiodine therapy for castration-resistant prostate cancer following prostate-specific membrane antigen promoter-mediated transfer of the human sodium iodide symporter
por: Gao, Xiao-Feng, et al.
Publicado: (2014)

Decreased Expression of Thyroglobulin and Sodium Iodide Symporter Genes in Hashimoto's Thyroiditis
por: Popławska-Kita, Anna, et al.
Publicado: (2014)

Physiological sodium concentrations enhance the iodide affinity of the Na(+)/I(−) symporter
por: Nicola, Juan P., et al.
Publicado: (2014)

Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer
por: Mansfield, D C, et al.
Publicado: (2016)

Sodium iodide symporter (NIS) in extrathyroidal malignancies: focus on breast and urological cancer
por: Micali, Salvatore, et al.
Publicado: (2014)

In Vivo Myoblasts Tracking Using the Sodium Iodide Symporter Gene Expression in Dogs
por: Punzón, Isabel, et al.
Publicado: (2020)

Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter
por: Read, Martin L., et al.
Publicado: (2022)

Enhancement of human sodium iodide symporter gene therapy for breast cancer by HDAC inhibitor mediated transcriptional modulation
por: Kelkar, Madhura G., et al.
Publicado: (2016)

Conserved charged amino acid residues in the extracellular region of sodium/iodide symporter are critical for iodide transport activity
por: Li, Chia-Cheng, et al.
Publicado: (2010)

Overexpression of Both Human Sodium Iodide Symporter (NIS) and BRG1-Bromodomain Synergistically Enhances Radioiodine Sensitivity by Stabilizing p53 through NPM1 Expression
por: Na, Juri, et al.
Publicado: (2023)

Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model
por: Ahn, S J, et al.
Publicado: (2010)

The Sodium Iodide Symporter (NIS) as an Imaging Reporter for Gene, Viral, and Cell-based Therapies
por: Penheiter, Alan R, et al.
Publicado: (2012)

Resveratrol Inhibits Sodium/Iodide Symporter Gene Expression and Function in Rat Thyroid Cells
por: Giuliani, Cesidio, et al.
Publicado: (2014)

Sodium Iodide Symporter PET and BLI Noninvasively Reveal Mesoangioblast Survival in Dystrophic Mice
por: Holvoet, Bryan, et al.
Publicado: (2015)

Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes
por: Spellerberg, Rebekka, et al.
Publicado: (2021)

Mechanisms of Sodium/Iodide Symporter-Mediated Mammary Gland Iodine Compensation during Lactation
por: Fu, Min, et al.
Publicado: (2022)

Evaluation of Lentiviral-Mediated Expression of Sodium Iodide Symporter in Anaplastic Thyroid Cancer and the Efficacy of In Vivo Imaging and Therapy
por: Ke, Chien-Chih, et al.
Publicado: (2011)

Codon-optimized Human Sodium Iodide Symporter (opt-hNIS) as a Sensitive Reporter and Efficient Therapeutic Gene
por: Kim, Young-Hwa, et al.
Publicado: (2015)

The Sodium Iodide Symporter (NIS) and Potential Regulators in Normal, Benign and Malignant Human Breast Tissue
por: Ryan, James, et al.
Publicado: (2011)

Sodium Iodide Symporter for Nuclear Molecular Imaging and Gene Therapy: From Bedside to Bench and Back
por: Ahn, Byeong-Cheol
Publicado: (2012)

Effect of thyroid statuses on sodium/iodide symporter (NIS) gene expression in the extrathyroidal tissues in mice
por: Harun-Or-Rashid, et al.
Publicado: (2010)

[(18)F]tetrafluoroborate as a PET tracer for the sodium/iodide symporter: the importance of specific activity
por: Khoshnevisan, Alex, et al.
Publicado: (2016)

Selumetinib Activity in Thyroid Cancer Cells: Modulation of Sodium Iodide Symporter and Associated miRNAs
por: Wächter, Sabine, et al.
Publicado: (2018)

Pro-tumorigenic non-pump function of sodium iodide symporter: A reimagined Trojan horse?
por: Feng, Fang, et al.
Publicado: (2019)

Prognostic Significance of Sodium Iodide Symporter and Deiodinase Enzymes mRNA Expression in Gastric Cancer
por: Mishra, Alok, et al.
Publicado: (2020)

Basolateral Sorting of the Sodium/Iodide Symporter Is Mediated by Adaptor Protein 1 Clathrin Adaptor Complexes
por: Koumarianou, Petrina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_amfffc0p42sipbkscpg4f95b9f