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The Replacement of 10 Non-Conserved Residues in the Core Protein of JFH-1 Hepatitis C Virus Improves Its Assembly and Secretion

Hepatitis C virus (HCV) assembly is still poorly understood. It is thought that trafficking of the HCV core protein to the lipid droplet (LD) surface is essential for its multimerization and association with newly synthesized HCV RNA to form the viral nucleocapsid. We carried out a mapping analysis...

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Detalles Bibliográficos
Autores principales:	Etienne, Loïc, Blanchard, Emmanuelle, Boyer, Audrey, Desvignes, Virginie, Gaillard, Julien, Meunier, Jean-Christophe, Roingeard, Philippe, Hourioux, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560444/ https://www.ncbi.nlm.nih.gov/pubmed/26339783 http://dx.doi.org/10.1371/journal.pone.0137182

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