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Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort
The mitochondrial genome encodes for the synthesis of 13 proteins that are essential for the oxidative phosphorylation (OXPHOS) system. Inherited variation in mitochondrial genes may influence cancer development through changes in mitochondrial proteins, altering the OXPHOS process, and promoting th...
Autores principales: | Li, Yuqing, Beckman, Kenneth B., Caberto, Christian, Kazma, Remi, Lum-Jones, Annette, Haiman, Christopher A., Marchand, Loïc Le, Stram, Daniel O., Saxena, Richa, Cheng, Iona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560485/ https://www.ncbi.nlm.nih.gov/pubmed/26340450 http://dx.doi.org/10.1371/journal.pone.0136796 |
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