1,25(OH)(2)D(3) Promotes the Efficacy of CD28 Costimulation Blockade by Abatacept

Inhibition of the CD28:CD80/CD86 T cell costimulatory pathway has emerged as an effective strategy for the treatment of T cell–mediated inflammatory diseases. However, patient responses to CD28-ligand blockade by abatacept (CTLA-4-Ig) in conditions such as rheumatoid arthritis are variable and often...

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Detalles Bibliográficos
Autores principales: Gardner, David H., Jeffery, Louisa E., Soskic, Blagoje, Briggs, Zoe, Hou, Tie Zheng, Raza, Karim, Sansom, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2015
Materias:
Immune Regulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560489/
https://www.ncbi.nlm.nih.gov/pubmed/26276872
http://dx.doi.org/10.4049/jimmunol.1500306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560489/
https://www.ncbi.nlm.nih.gov/pubmed/26276872
http://dx.doi.org/10.4049/jimmunol.1500306

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