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Lipoxin A(4) Attenuates Constitutive and TGF-β1–Dependent Profibrotic Activity in Human Lung Myofibroblasts
Idiopathic pulmonary fibrosis (IPF) is a common, progressive, and invariably lethal interstitial lung disease with no effective therapy. The key cell driving the development of fibrosis is the myofibroblast. Lipoxin A(4) (LXA(4)) is an anti-inflammatory lipid, important in the resolution of inflamma...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560490/ https://www.ncbi.nlm.nih.gov/pubmed/26276873 http://dx.doi.org/10.4049/jimmunol.1500936 |