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Lipoxin A(4) Attenuates Constitutive and TGF-β1–Dependent Profibrotic Activity in Human Lung Myofibroblasts

Idiopathic pulmonary fibrosis (IPF) is a common, progressive, and invariably lethal interstitial lung disease with no effective therapy. The key cell driving the development of fibrosis is the myofibroblast. Lipoxin A(4) (LXA(4)) is an anti-inflammatory lipid, important in the resolution of inflamma...

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Detalles Bibliográficos
Autores principales:	Roach, Katy M., Feghali-Bostwick, Carol A., Amrani, Yassine, Bradding, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2015
Materias:	Molecular and Structural Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560490/ https://www.ncbi.nlm.nih.gov/pubmed/26276873 http://dx.doi.org/10.4049/jimmunol.1500936

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