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Insight into the mechanism of polyphenols on the activity of HMGR by molecular docking

Statins are hypolipidemic drugs that are effective in the treatment of hypercholesterolemia by attenuating cholesterol synthesis in the liver via competitive inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Recently, dietary changes associated with drug therapy have garnered...

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Detalles Bibliográficos
Autores principales:	Islam, Barira, Sharma, Charu, Adem, Abdu, Aburawi, Elhadi, Ojha, Shreesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560516/ https://www.ncbi.nlm.nih.gov/pubmed/26357462 http://dx.doi.org/10.2147/DDDT.S86705

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