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High glucose inhibits ClC-2 chloride channels and attenuates cell migration of rat keratinocytes

BACKGROUND: Accumulating evidence has demonstrated that migration of keratinocytes is critical to wound epithelialization, and defects of this function result in chronic delayed-healing wounds in diabetes mellitus patients, and the migration has been proved to be associated with volume-activated chl...

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Detalles Bibliográficos
Autores principales: Pan, Fuqiang, Guo, Rui, Cheng, Wenguang, Chai, Linlin, Wang, Wenping, Cao, Chuan, Li, Shirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560522/
https://www.ncbi.nlm.nih.gov/pubmed/26355894
http://dx.doi.org/10.2147/DDDT.S84628