Cargando…

Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids

Natural flavonoids such as genistein, kaempferol and daidzein were previously found to be able to reduce efficiency of glycosaminoglycan synthesis in cells of patients suffering from mucopolysaccharidoses, inherited metabolic diseases with often brain disease symptoms. This feature was employed to t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moskot, Marta, Jakóbkiewicz-Banecka, Joanna, Smolińska, Elwira, Banecki, Bogdan, Węgrzyn, Grzegorz, Gabig-Cimińska, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560762/ https://www.ncbi.nlm.nih.gov/pubmed/26209177 http://dx.doi.org/10.1007/s11011-015-9705-x

Ejemplares similares

Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
por: Moskot, Marta, et al.
Publicado: (2015)

Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
por: Moskot, Marta, et al.
Publicado: (2015)

Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
por: Moskot, Marta, et al.
Publicado: (2016)

Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
por: Moskot, Marta, et al.
Publicado: (2016)

Abnormal Sphingolipid World in Inflammation Specific for Lysosomal Storage Diseases and Skin Disorders
por: Moskot, Marta, et al.
Publicado: (2018)

Molecular action of isoflavone genistein in the human epithelial cell line HaCaT
por: Smolińska, Elwira, et al.
Publicado: (2018)

Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways
por: Mozolewski, Paweł, et al.
Publicado: (2017)

Models in the Research Process of Psoriasis
por: Bocheńska, Katarzyna, et al.
Publicado: (2017)

Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases
por: Jakóbkiewicz-Banecka, Joanna, et al.
Publicado: (2013)

The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins
por: Grabowski, Michał, et al.
Publicado: (2016)

Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations
por: Bocheńska, Katarzyna, et al.
Publicado: (2021)

The Role of Dimethyl Sulfoxide (DMSO) in Gene Expression Modulation and Glycosaminoglycan Metabolism in Lysosomal Storage Disorders on an Example of Mucopolysaccharidosis
por: Moskot, Marta, et al.
Publicado: (2019)

Effect of Silicone on the Collagen Fibrillogenesis and Stability
por: Kadziński, Leszek, et al.
Publicado: (2015)

Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I
por: Węsierska, Magdalena, et al.
Publicado: (2022)

Synthetic genistein derivatives as modulators of glycosaminoglycan storage
por: Kloska, Anna, et al.
Publicado: (2012)

Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
por: Kloska, Anna, et al.
Publicado: (2020)

Lipids and Lipid Mediators Associated with the Risk and Pathology of Ischemic Stroke
por: Kloska, Anna, et al.
Publicado: (2020)

Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis
por: Bocheńska, Katarzyna, et al.
Publicado: (2019)

Correction: Bocheńska, K. et al. Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis. Int. J. Mol. Sci. 2019, 20, 2255
por: Bocheńska, Katarzyna, et al.
Publicado: (2020)

Effects of flavonoids on glycosaminoglycan synthesis: implications for substrate reduction therapy in Sanfilippo disease and other mucopolysaccharidoses
por: Kloska, Anna, et al.
Publicado: (2011)

Unbalanced Sphingolipid Metabolism and Its Implications for the Pathogenesis of Psoriasis
por: Bocheńska, Katarzyna, et al.
Publicado: (2020)

Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models
por: Bocheńska, Katarzyna, et al.
Publicado: (2021)

Molecular treatment trajectories within psoriatic T lymphocytes: a mini review
por: Kuczyńska, Martyna, et al.
Publicado: (2023)

Genistein-mediated inhibition of glycosaminoglycan synthesis, which corrects storage in cells of patients suffering from mucopolysaccharidoses, acts by influencing an epidermal growth factor-dependent pathway
por: Jakóbkiewicz-Banecka, Joanna, et al.
Publicado: (2009)

Dosage Compensation in Females with X-Linked Metabolic Disorders
por: Juchniewicz, Patrycja, et al.
Publicado: (2021)

Sample processing for DNA chip array-based analysis of enterohemorrhagic Escherichia coli (EHEC)
por: Basselet, Pascal, et al.
Publicado: (2008)

Prevalence of polymorphisms in OPG, RANKL and RANK as potential markers for Charcot arthropathy development
por: Bruhn-Olszewska, Bożena, et al.
Publicado: (2017)

Murine Fibroblasts and Primary Hepatocytes as Tools When Studying the Efficacy of Potential Therapies for Mucopolysaccharidosis Type I
por: Węsierska, Magdalena, et al.
Publicado: (2022)

Atypical microbial infections of digestive tract may contribute to diarrhea in mucopolysaccharidosis patients: a MPS I case study
por: Węgrzyn, Grzegorz, et al.
Publicado: (2005)

Two-year follow-up of Sanfilippo Disease patients treated with a genistein-rich isoflavone extract: Assessment of effects on cognitive functions and general status of patients
por: Piotrowska, Ewa, et al.
Publicado: (2011)

Developing nucleic acid-based electrical detection systems
por: Gabig-Ciminska, Magdalena
Publicado: (2006)

Oxidative Stress as an Important Contributor to the Pathogenesis of Psoriasis
por: Pleńkowska, Joanna, et al.
Publicado: (2020)

X-chromosome inactivation patterns depend on age and tissue but not conception method in humans
por: Juchniewicz, Patrycja, et al.
Publicado: (2023)

Editorial: Innovative integrated immuno—and inflammopharmacology in reference to autoimmune skin diseases
por: Gabig-Cimińska, Magdalena, et al.
Publicado: (2023)

Drug-resistant epilepsia and fulminant valproate liver toxicity. Alpers-Huttenlocher syndrome in two children confirmed post mortem by identification of p.W748S mutation in POLG gene
por: Pronicka, Ewa, et al.
Publicado: (2011)

Post mortem identification of deoxyguanosine kinase (DGUOK) gene mutations combined with impaired glucose homeostasis and iron overload features in four infants with severe progressive liver failure
por: Pronicka, Ewa, et al.
Publicado: (2010)

The mRNA level of the transforming growth factor β1 gene, but not the amount of the gene product, can be considered as a potential prognostic parameter in inflammatory bowel diseases in children
por: Liberek, Anna, et al.
Publicado: (2012)

A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
por: Słomiński, Bartosz, et al.
Publicado: (2020)

Global Changes of 5-mC/5h-mC Ratio and Methylation of Adiponectin and Leptin Gene in Placenta Depending on Mode of Delivery
por: Słabuszewska-Jóźwiak, Aneta, et al.
Publicado: (2021)

Identification of pathogenic microbial cells and spores by electrochemical detection on a biochip
por: Gabig-Ciminska, Magdalena, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_7817tdt35rpvp794mo5hss90qv