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Optical control of NMDA receptors with a diffusible photoswitch
N-methyl-D-aspartate receptors (NMDARs) play a central role in synaptic plasticity, learning and memory, and are implicated in various neuronal disorders. We synthesized a diffusible photochromic glutamate analogue, azobenzene-triazole-glutamate (ATG), which is specific for NMDARs and functions as a...
Autores principales: | Laprell, Laura, Repak, Emilienne, Franckevicius, Vilius, Hartrampf, Felix, Terhag, Jan, Hollmann, Michael, Sumser, Martin, Rebola, Nelson, DiGregorio, David A., Trauner, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560805/ https://www.ncbi.nlm.nih.gov/pubmed/26311290 http://dx.doi.org/10.1038/ncomms9076 |
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