Comparison of the pathogenesis of the highly passaged MCMV Smith strain with that of the low passaged MCMV HaNa1 isolate in BALB/c mice upon oronasal inoculation

Murine cytomegalovirus (MCMV) Smith strain is widely used in mouse models to study HCMV infections. Due to high serial passages, MCMV Smith has acquired genetic and biological changes. Therefore, a low passaged strain would be more relevant to develop mouse models. Here, the pathogenesis of an infec...

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Detalles Bibliográficos
Autores principales: Zhang, Shunchuan, Xiang, Jun, Van Doorsselaere, Jan, Nauwynck, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560884/
https://www.ncbi.nlm.nih.gov/pubmed/26340811
http://dx.doi.org/10.1186/s13567-015-0228-6

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