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Prosaposin activates the androgen receptor and potentiates resistance to endocrine treatment in breast cancer

INTRODUCTION: HOX genes play vital roles in growth and development, however, atypical redeployment of these genes is often associated with steroidal adaptability in endocrine cancers. We previously identified HOXC11 to be an indicator of poor response to hormonal therapy in breast cancer. In this st...

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Detalles Bibliográficos
Autores principales: Ali, Azlena, Creevey, Laura, Hao, Yuan, McCartan, Damian, O’Gaora, Peadar, Hill, Arnold, Young, Leonie, McIlroy, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560928/
https://www.ncbi.nlm.nih.gov/pubmed/26341737
http://dx.doi.org/10.1186/s13058-015-0636-6

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