Cargando…
Cannabinoid-based drugs targeting CB(1) and TRPV1, the sympathetic nervous system, and arthritis
Chronic inflammation in rheumatoid arthritis (RA) is accompanied by activation of the sympathetic nervous system, which can support the immune system to perpetuate inflammation. Several animal models of arthritis already demonstrated a profound influence of adrenergic signaling on the course of RA....
Autores principales: | Lowin, Torsten, Straub, Rainer H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561168/ https://www.ncbi.nlm.nih.gov/pubmed/26343051 http://dx.doi.org/10.1186/s13075-015-0743-x |
Ejemplares similares
-
The synthetic cannabinoid WIN55,212-2 mesylate decreases the production of inflammatory mediators in rheumatoid arthritis synovial fibroblasts by activating CB(2), TRPV1, TRPA1 and yet unidentified receptor targets
por: Lowin, Torsten, et al.
Publicado: (2016) -
Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner
por: Lowin, Torsten, et al.
Publicado: (2015) -
Components of the sympathetic nervous system as targets to modulate inflammation – rheumatoid arthritis synovial fibroblasts as neuron-like cells?
por: Cheng, Xinkun, et al.
Publicado: (2023) -
Integrins and their ligands in rheumatoid arthritis
por: Lowin, Torsten, et al.
Publicado: (2011) -
Expression of cannabinoid (CB1 and CB2) and cannabinoid-related receptors (TRPV1, GPR55, and PPARα) in the synovial membrane of the horse metacarpophalangeal joint
por: Zamith Cunha, Rodrigo, et al.
Publicado: (2023)