Increased expression of PHD3 represses the HIF-1 signaling pathway and contributes to poor neovascularization in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is known as one of the most malignant potential diseases with poor neovascularization. By comparing PDAC to hepatocellular carcinoma (HCC), which is well vascularized, we investigated the mechanisms and tumor biological significance of the poor neo...

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Detalles Bibliográficos
Autores principales: Tanaka, Takayuki, Li, Tao-Sheng, Urata, Yoshishige, Goto, Shinji, Ono, Yusuke, Kawakatsu, Miho, Matsushima, Hajime, Hirabaru, Masataka, Adachi, Tomohiko, Kitasato, Amane, Takatsuki, Mitsuhisa, Kuroki, Tamotsu, Eguchi, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2014
Materias:
Original Article—Liver, Pancreas, and Biliary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561234/
https://www.ncbi.nlm.nih.gov/pubmed/25542265
http://dx.doi.org/10.1007/s00535-014-1030-3

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