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A widespread role of the motif environment in transcription factor binding across diverse protein families

Transcriptional regulation requires the binding of transcription factors (TFs) to short sequence-specific DNA motifs, usually located at the gene regulatory regions. Interestingly, based on a vast amount of data accumulated from genomic assays, it has been shown that only a small fraction of all pot...

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Detalles Bibliográficos
Autores principales: Dror, Iris, Golan, Tamar, Levy, Carmit, Rohs, Remo, Mandel-Gutfreund, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561487/
https://www.ncbi.nlm.nih.gov/pubmed/26160164
http://dx.doi.org/10.1101/gr.184671.114