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A widespread role of the motif environment in transcription factor binding across diverse protein families
Transcriptional regulation requires the binding of transcription factors (TFs) to short sequence-specific DNA motifs, usually located at the gene regulatory regions. Interestingly, based on a vast amount of data accumulated from genomic assays, it has been shown that only a small fraction of all pot...
Autores principales: | Dror, Iris, Golan, Tamar, Levy, Carmit, Rohs, Remo, Mandel-Gutfreund, Yael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561487/ https://www.ncbi.nlm.nih.gov/pubmed/26160164 http://dx.doi.org/10.1101/gr.184671.114 |
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