Cargando…
SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells
SETDB1, a histone methyltransferase responsible for methylation of histone H3 lysine 9 (H3K9), is involved in maintenance of embryonic stem (ES) cells and early embryonic development of the mouse. However, how SETDB1 regulates gene expression during development is largely unknown. Here, we character...
Autores principales: | Fei, Qi, Yang, Xiaoqin, Jiang, Hua, Wang, Qian, Yu, Yanyan, Yu, Yiling, Yi, Wei, Zhou, Shaolian, Chen, Taiping, Lu, Chris, Atadja, Peter, Liu, Xiaole Shirley, Li, En, Zhang, Yong, Shou, Jianyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561491/ https://www.ncbi.nlm.nih.gov/pubmed/26160163 http://dx.doi.org/10.1101/gr.177576.114 |
Ejemplares similares
-
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
por: Fei, Qi, et al.
Publicado: (2015) -
Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing
por: Mochizuki, Kentaro, et al.
Publicado: (2021) -
PRC1 preserves epidermal tissue integrity independently of PRC2
por: Cohen, Idan, et al.
Publicado: (2019) -
Independent domains for recruitment of PRC1 and PRC2 by human XIST
por: Dixon-McDougall, Thomas, et al.
Publicado: (2021) -
Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse
por: Kim, Jeesun, et al.
Publicado: (2016)