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The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing
RNA-seq by poly(A) selection is currently the most common protocol for whole transcriptome sequencing as it provides a broad, detailed, and accurate view of the RNA landscape. Unfortunately, the utility of poly(A) libraries is greatly limited when the input RNA is degraded, which is the norm for res...
Autores principales: | Cieslik, Marcin, Chugh, Rashmi, Wu, Yi-Mi, Wu, Ming, Brennan, Christine, Lonigro, Robert, Su, Fengyun, Wang, Rui, Siddiqui, Javed, Mehra, Rohit, Cao, Xuhong, Lucas, David, Chinnaiyan, Arul M., Robinson, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561495/ https://www.ncbi.nlm.nih.gov/pubmed/26253700 http://dx.doi.org/10.1101/gr.189621.115 |
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