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Regulation of mitochondrial morphology and function by Stearoylation of TfR1

Mitochondria are involved in a variety of cellular functions including ATP production, amino acid and lipid biogenesis and breakdown, signaling and apoptosis(1-3). Mitochondrial dysfunction has been linked to neurodegenerative diseases, cancer, and aging(4). Although transcriptional mechanisms regul...

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Detalles Bibliográficos
Autores principales: Senyilmaz, Deniz, Virtue, Sam, Xu, Xiaojun, Tan, Chong Yew, Griffin, Julian L, Miller, Aubry K., Vidal-Puig, Antonio, Teleman, Aurelio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561519/
https://www.ncbi.nlm.nih.gov/pubmed/26214738
http://dx.doi.org/10.1038/nature14601