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Insights into Regulation of the miR-17-92 Cluster of miRNAs in Cancer
Overexpression of the miR-17-92 cluster is a key oncogenic event in various cancer types. The oncogenic effect of the miR-17-92 cluster is enhanced by cooperation between its members in targeting tumor-suppressive proteins and pathways such as PTEN and TGFβ signaling. However, in the case of miR-19a...
Autores principales: | Fuziwara, Cesar Seigi, Kimura, Edna Teruko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561802/ https://www.ncbi.nlm.nih.gov/pubmed/26442266 http://dx.doi.org/10.3389/fmed.2015.00064 |
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