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A Simple and Sensitive Method to Quantify Biodegradable Nanoparticle Biodistribution using Europium Chelates

The biodistribution of biodegradable nanoparticles can be difficult to quantify. We report a method using time resolved fluorescence (TRF) from a lanthanide chelate to minimize background autofluorescence and maximize the signal to noise ratio to detect biodegradable nanoparticle distribution in mic...

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Detalles Bibliográficos
Autores principales: Crawford, Lindsey, Higgins, Jaclyn, Putnam, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561907/
https://www.ncbi.nlm.nih.gov/pubmed/26346817
http://dx.doi.org/10.1038/srep13177