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Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions
BACKGROUND: CTCF and BORIS (CTCFL), two paralogous mammalian proteins sharing nearly identical DNA binding domains, are thought to function in a mutually exclusive manner in DNA binding and transcriptional regulation. RESULTS: Here we show that these two proteins co-occupy a specific subset of regul...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562119/ https://www.ncbi.nlm.nih.gov/pubmed/26268681 http://dx.doi.org/10.1186/s13059-015-0736-8 |