Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions

BACKGROUND: CTCF and BORIS (CTCFL), two paralogous mammalian proteins sharing nearly identical DNA binding domains, are thought to function in a mutually exclusive manner in DNA binding and transcriptional regulation. RESULTS: Here we show that these two proteins co-occupy a specific subset of regul...

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Detalles Bibliográficos
Autores principales: Pugacheva, Elena M., Rivero-Hinojosa, Samuel, Espinoza, Celso A., Méndez-Catalá, Claudia Fabiola, Kang, Sungyun, Suzuki, Teruhiko, Kosaka-Suzuki, Natsuki, Robinson, Susan, Nagarajan, Vijayaraj, Ye, Zhen, Boukaba, Abdelhalim, Rasko, John E. J., Strunnikov, Alexander V., Loukinov, Dmitri, Ren, Bing, Lobanenkov, Victor V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562119/
https://www.ncbi.nlm.nih.gov/pubmed/26268681
http://dx.doi.org/10.1186/s13059-015-0736-8

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