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Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model

The results of this experiment suggested that electroacupuncture promotes the endothelialization of liver endothelial progenitor cells (EPCs) for mice in D-gal model and improves the repair of vascular endothelial function, as well as increasing the vascular endothelial growth factor (VEGF) expressi...

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Detalles Bibliográficos
Autor principal: Wen, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562170/
https://www.ncbi.nlm.nih.gov/pubmed/26379754
http://dx.doi.org/10.1155/2015/972749
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author Wen, Mei
author_facet Wen, Mei
author_sort Wen, Mei
collection PubMed
description The results of this experiment suggested that electroacupuncture promotes the endothelialization of liver endothelial progenitor cells (EPCs) for mice in D-gal model and improves the repair of vascular endothelial function, as well as increasing the vascular endothelial growth factor (VEGF) expression in liver tissue fluorescence and KL protein levels. Also, it reduces the malondialdehyde (MDA) activity and delays vascular aging and even overall aging. Results showed that the in vivo fluorescence intensity for D-gal EA group was significantly lower than that of D-gal group, P < 0.05; VEGF fluorescence expression in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; KL protein content in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; MDA activity for D-gal EA group was significantly lower than that for D-gal group, P < 0.05.
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spelling pubmed-45621702015-09-15 Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model Wen, Mei Evid Based Complement Alternat Med Research Article The results of this experiment suggested that electroacupuncture promotes the endothelialization of liver endothelial progenitor cells (EPCs) for mice in D-gal model and improves the repair of vascular endothelial function, as well as increasing the vascular endothelial growth factor (VEGF) expression in liver tissue fluorescence and KL protein levels. Also, it reduces the malondialdehyde (MDA) activity and delays vascular aging and even overall aging. Results showed that the in vivo fluorescence intensity for D-gal EA group was significantly lower than that of D-gal group, P < 0.05; VEGF fluorescence expression in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; KL protein content in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; MDA activity for D-gal EA group was significantly lower than that for D-gal group, P < 0.05. Hindawi Publishing Corporation 2015 2015-08-25 /pmc/articles/PMC4562170/ /pubmed/26379754 http://dx.doi.org/10.1155/2015/972749 Text en Copyright © 2015 Mei Wen. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wen, Mei
Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title_full Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title_fullStr Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title_full_unstemmed Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title_short Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
title_sort intervention effect of electroacupuncture combined with epcs transplantation on the mice in aging model
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562170/
https://www.ncbi.nlm.nih.gov/pubmed/26379754
http://dx.doi.org/10.1155/2015/972749
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