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Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562184/ https://www.ncbi.nlm.nih.gov/pubmed/26380326 http://dx.doi.org/10.1155/2015/832057 |
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author | Campos, João Henrique Soares, Rodrigo Pedro Ribeiro, Kleber Cronemberger Andrade, André Batista, Wagner Luiz Torrecilhas, Ana Claudia |
author_facet | Campos, João Henrique Soares, Rodrigo Pedro Ribeiro, Kleber Cronemberger Andrade, André Batista, Wagner Luiz Torrecilhas, Ana Claudia |
author_sort | Campos, João Henrique |
collection | PubMed |
description | Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases. |
format | Online Article Text |
id | pubmed-4562184 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-45621842015-09-15 Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases Campos, João Henrique Soares, Rodrigo Pedro Ribeiro, Kleber Cronemberger Andrade, André Batista, Wagner Luiz Torrecilhas, Ana Claudia J Immunol Res Review Article Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases. Hindawi Publishing Corporation 2015 2015-08-25 /pmc/articles/PMC4562184/ /pubmed/26380326 http://dx.doi.org/10.1155/2015/832057 Text en Copyright © 2015 João Henrique Campos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Campos, João Henrique Soares, Rodrigo Pedro Ribeiro, Kleber Cronemberger Andrade, André Batista, Wagner Luiz Torrecilhas, Ana Claudia Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title_full | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title_fullStr | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title_full_unstemmed | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title_short | Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases |
title_sort | extracellular vesicles: role in inflammatory responses and potential uses in vaccination in cancer and infectious diseases |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562184/ https://www.ncbi.nlm.nih.gov/pubmed/26380326 http://dx.doi.org/10.1155/2015/832057 |
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