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Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases

Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their b...

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Detalles Bibliográficos
Autores principales: Campos, João Henrique, Soares, Rodrigo Pedro, Ribeiro, Kleber, Cronemberger Andrade, André, Batista, Wagner Luiz, Torrecilhas, Ana Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562184/
https://www.ncbi.nlm.nih.gov/pubmed/26380326
http://dx.doi.org/10.1155/2015/832057
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author Campos, João Henrique
Soares, Rodrigo Pedro
Ribeiro, Kleber
Cronemberger Andrade, André
Batista, Wagner Luiz
Torrecilhas, Ana Claudia
author_facet Campos, João Henrique
Soares, Rodrigo Pedro
Ribeiro, Kleber
Cronemberger Andrade, André
Batista, Wagner Luiz
Torrecilhas, Ana Claudia
author_sort Campos, João Henrique
collection PubMed
description Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases.
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spelling pubmed-45621842015-09-15 Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases Campos, João Henrique Soares, Rodrigo Pedro Ribeiro, Kleber Cronemberger Andrade, André Batista, Wagner Luiz Torrecilhas, Ana Claudia J Immunol Res Review Article Almost all cells and organisms release membrane structures containing proteins, lipids, and nucleic acids called extracellular vesicles (EVs), which have a wide range of functions concerning intercellular communication and signaling events. Recently, the characterization and understanding of their biological role have become a main research area due to their potential role in vaccination, as biomarkers antigens, early diagnostic tools, and therapeutic applications. Here, we will overview the recent advances and studies of Evs shed by tumor cells, bacteria, parasites, and fungi, focusing on their inflammatory role and their potential use in vaccination and diagnostic of cancer and infectious diseases. Hindawi Publishing Corporation 2015 2015-08-25 /pmc/articles/PMC4562184/ /pubmed/26380326 http://dx.doi.org/10.1155/2015/832057 Text en Copyright © 2015 João Henrique Campos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Campos, João Henrique
Soares, Rodrigo Pedro
Ribeiro, Kleber
Cronemberger Andrade, André
Batista, Wagner Luiz
Torrecilhas, Ana Claudia
Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title_full Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title_fullStr Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title_full_unstemmed Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title_short Extracellular Vesicles: Role in Inflammatory Responses and Potential Uses in Vaccination in Cancer and Infectious Diseases
title_sort extracellular vesicles: role in inflammatory responses and potential uses in vaccination in cancer and infectious diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562184/
https://www.ncbi.nlm.nih.gov/pubmed/26380326
http://dx.doi.org/10.1155/2015/832057
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