A double-blind, randomised, placebo-controlled study of roxithromycin and doxycycline combination, roxithromycin alone, or matching placebo for 12 weeks in adults with frequent exacerbations of chronic obstructive pulmonary disease

BACKGROUND: Azithromycin prophylaxis has been shown to reduce COPD exacerbations but there is poor evidence for other antibiotics. We compared exacerbation rates in COPD patients with a history of frequent exacerbations (at least three moderate or severe COPD exacerbations in the past two years) dur...

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Detalles Bibliográficos
Autores principales: Shafuddin, Eskandarain, Mills, Graham D., Holmes, Mark D., Poole, Phillippa J., Mullins, Peter R., Black, Peter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562194/
https://www.ncbi.nlm.nih.gov/pubmed/26346300
http://dx.doi.org/10.1186/s12952-015-0034-8

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