Cargando…

Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study

BACKGROUND: The combination of milbemycin oxime–praziquantel is widely used against the most common tapeworms and roundworms affecting cats. New veterinary presentations of this combination have recently been approved. OBJECTIVE: The objective of this study was to compare the palatability of two pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Bernachon, N., McGahie, D., Corvaisier, D., Benizeau, E., Crastes, N., Chaix, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562452/
https://www.ncbi.nlm.nih.gov/pubmed/26392882
http://dx.doi.org/10.1136/vetreco-2014-000080
_version_ 1782389165827031040
author Bernachon, N.
McGahie, D.
Corvaisier, D.
Benizeau, E.
Crastes, N.
Chaix, G.
author_facet Bernachon, N.
McGahie, D.
Corvaisier, D.
Benizeau, E.
Crastes, N.
Chaix, G.
author_sort Bernachon, N.
collection PubMed
description BACKGROUND: The combination of milbemycin oxime–praziquantel is widely used against the most common tapeworms and roundworms affecting cats. New veterinary presentations of this combination have recently been approved. OBJECTIVE: The objective of this study was to compare the palatability of two products using this combination, Milpro(®) and Milbemax(®). METHODS: In all, 20 adult cats and 20 kittens were offered each product according to a randomisation table using a blinded crossover design. Prehension from the bowl, prehension from the hand and total consumption were assessed. RESULTS: Both presentations were very well tolerated in adult cats and kittens. Total prehension in adult cats and kittens was 100 and 45 per cent, respectively, for Milpro(®), and 95 and 30 per cent, respectively, for Milbemax(®). The percentages of adult cats and kittens which swallowed the pill after taking it into their mouth (total spontaneous consumption) were respectively 40 and 45 per cent for Milpro(®), and 35 and 20 per cent for Milbemax(®). CONCLUSION: In this study, both presentations were highly attractive to cats and their respective coatings successfully covered the unpleasant odour of praziquantel, which usually repels cats. These results indicate that the palatability of Milpro(®) is at least as good as Milbemax(®) and both tablets are well accepted by adult cats and kittens.
format Online
Article
Text
id pubmed-4562452
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-45624522015-09-21 Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study Bernachon, N. McGahie, D. Corvaisier, D. Benizeau, E. Crastes, N. Chaix, G. Vet Rec Open Research BACKGROUND: The combination of milbemycin oxime–praziquantel is widely used against the most common tapeworms and roundworms affecting cats. New veterinary presentations of this combination have recently been approved. OBJECTIVE: The objective of this study was to compare the palatability of two products using this combination, Milpro(®) and Milbemax(®). METHODS: In all, 20 adult cats and 20 kittens were offered each product according to a randomisation table using a blinded crossover design. Prehension from the bowl, prehension from the hand and total consumption were assessed. RESULTS: Both presentations were very well tolerated in adult cats and kittens. Total prehension in adult cats and kittens was 100 and 45 per cent, respectively, for Milpro(®), and 95 and 30 per cent, respectively, for Milbemax(®). The percentages of adult cats and kittens which swallowed the pill after taking it into their mouth (total spontaneous consumption) were respectively 40 and 45 per cent for Milpro(®), and 35 and 20 per cent for Milbemax(®). CONCLUSION: In this study, both presentations were highly attractive to cats and their respective coatings successfully covered the unpleasant odour of praziquantel, which usually repels cats. These results indicate that the palatability of Milpro(®) is at least as good as Milbemax(®) and both tablets are well accepted by adult cats and kittens. BMJ Publishing Group 2014-12-30 /pmc/articles/PMC4562452/ /pubmed/26392882 http://dx.doi.org/10.1136/vetreco-2014-000080 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Research
Bernachon, N.
McGahie, D.
Corvaisier, D.
Benizeau, E.
Crastes, N.
Chaix, G.
Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title_full Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title_fullStr Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title_full_unstemmed Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title_short Comparative palatability of two veterinary dewormers (Milpro(®) and Milbemax(®)): a blinded randomised crossover cat study
title_sort comparative palatability of two veterinary dewormers (milpro(®) and milbemax(®)): a blinded randomised crossover cat study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562452/
https://www.ncbi.nlm.nih.gov/pubmed/26392882
http://dx.doi.org/10.1136/vetreco-2014-000080
work_keys_str_mv AT bernachonn comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy
AT mcgahied comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy
AT corvaisierd comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy
AT benizeaue comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy
AT crastesn comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy
AT chaixg comparativepalatabilityoftwoveterinarydewormersmilproandmilbemaxablindedrandomisedcrossovercatstudy