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Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture
Clinical use of umbilical cord blood has typically been limited by the need to expand hematopoietic stem and progenitor cells (HSPC) ex vivo. This expansion is challenging due to the accumulation of secreted signaling factors in the culture that have a negative regulatory effect on HSPC output. Stra...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562642/ https://www.ncbi.nlm.nih.gov/pubmed/26348930 http://dx.doi.org/10.1371/journal.pone.0137392 |