A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures

CCDC39 and CCDC40 were first identified as causative mutations in primary ciliary dyskinesia patients; cilia from patients show disorganized microtubules, and they are missing both N-DRC and inner dynein arms proteins. In Chlamydomonas, we used immunoblots and microtubule sliding assays to show that...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Huawen, Zhang, Zhengyan, Guo, Suyang, Chen, Fan, Kessler, Jonathan M., Wang, Yan Mei, Dutcher, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562644/
https://www.ncbi.nlm.nih.gov/pubmed/26348919
http://dx.doi.org/10.1371/journal.pgen.1005508

Ejemplares similares

Ejemplares similares