Genome-Wide Scan for Visceral Leishmaniasis in Mixed-Breed Dogs Identifies Candidate Genes Involved in T Helper Cells and Macrophage Signaling

We conducted a genome-wide scan for visceral leishmaniasis in mixed-breed dogs from a highly endemic area in Brazil using 149,648 single nucleotide polymorphism (SNP) markers genotyped in 20 cases and 28 controls. Using a mixed model approach, we found two candidate loci on canine autosomes 1 and 2....

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Detalles Bibliográficos
Autores principales: Utsunomiya, Yuri T., Ribeiro, Érica S., Quintal, Amanda P. N., Sangalli, Juliano R., Gazola, Valquiria R., Paula, Henrique B., Trinconi, Cristiana M., Lima, Valéria M. F., Perri, Silvia H. V., Taylor, Jeremy F., Schnabel, Robert D., Sonstegard, Tad S., Garcia, José F., Nunes, Cáris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562658/
https://www.ncbi.nlm.nih.gov/pubmed/26348501
http://dx.doi.org/10.1371/journal.pone.0136749

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