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Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice1,2,3

Loss-of-function mutations in progranulin (GRN) are one of the most common genetic causes of frontotemporal dementia (FTD), a progressive, fatal neurodegenerative disorder with no available disease-modifying treatments. Through haploinsufficiency, these mutations reduce levels of progranulin, a prot...

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Detalles Bibliográficos
Autores principales:	Arrant, Andrew E., Patel, Aashka R., Roberson, Erik D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2015
Materias:	Negative Results
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562684/ https://www.ncbi.nlm.nih.gov/pubmed/26361634 http://dx.doi.org/10.1523/ENEURO.0061-14.2015

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