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Cationic polyelectrolyte-mediated delivery of antisense morpholino oligonucleotides for exon-skipping in vitro and in mdx mice

In this study, we investigated a series of cationic polyelectrolytes (PEs) with different size and composition for their potential to improve delivery of an antisense phosphorodiamidate morpholino oligomer (PMO) both in vitro and in vivo. The results showed that the poly(diallyldimethylammonium chlo...

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Detalles Bibliográficos
Autores principales:	Wang, Mingxing, Wu, Bo, Tucker, Jason D, Lu, Peijuan, Lu, Qilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562748/ https://www.ncbi.nlm.nih.gov/pubmed/26366082 http://dx.doi.org/10.2147/IJN.S89910

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