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Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer

BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search...

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Autores principales: Wang, Rong-jiang, Tang, Jian-er, Chen, Yu, Gao, Jian-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562756/
https://www.ncbi.nlm.nih.gov/pubmed/26366096
http://dx.doi.org/10.2147/OTT.S88528
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author Wang, Rong-jiang
Tang, Jian-er
Chen, Yu
Gao, Jian-guo
author_facet Wang, Rong-jiang
Tang, Jian-er
Chen, Yu
Gao, Jian-guo
author_sort Wang, Rong-jiang
collection PubMed
description BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search of PubMed database and EMBASE database up to April 2015. A random effects model was used to calculate the summary relative risks (RRs) and their corresponding 95% confidence intervals (CIs). RESULTS: Twenty-seven epidemiological studies (18 case–control studies and nine cohort studies) were included in the final analysis. The pooled RRs of prostate cancer were 0.94 (95% CI 0.85–1.05, P=0.285), 1.13 (95% CI 0.98–1.30, P=0.095), 0.96 (95% CI 0.81–1.14, P=0.672), 1.06 (95% CI 0.96–1.18, P=0.254), and 1.04 (95% CI 0.91–1.18, P=0.590) for dietary fiber, whole grains, carbohydrate, GI, and GL, respectively. There was no evidence of significant publication bias based on the Begg’s test and Egger’s test. CONCLUSION: The findings of this meta-analysis indicate that, based on available information, dietary fiber, whole grains, carbohydrate, GI, and GL are not associated with the risk of prostate cancer.
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spelling pubmed-45627562015-09-11 Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer Wang, Rong-jiang Tang, Jian-er Chen, Yu Gao, Jian-guo Onco Targets Ther Original Research BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search of PubMed database and EMBASE database up to April 2015. A random effects model was used to calculate the summary relative risks (RRs) and their corresponding 95% confidence intervals (CIs). RESULTS: Twenty-seven epidemiological studies (18 case–control studies and nine cohort studies) were included in the final analysis. The pooled RRs of prostate cancer were 0.94 (95% CI 0.85–1.05, P=0.285), 1.13 (95% CI 0.98–1.30, P=0.095), 0.96 (95% CI 0.81–1.14, P=0.672), 1.06 (95% CI 0.96–1.18, P=0.254), and 1.04 (95% CI 0.91–1.18, P=0.590) for dietary fiber, whole grains, carbohydrate, GI, and GL, respectively. There was no evidence of significant publication bias based on the Begg’s test and Egger’s test. CONCLUSION: The findings of this meta-analysis indicate that, based on available information, dietary fiber, whole grains, carbohydrate, GI, and GL are not associated with the risk of prostate cancer. Dove Medical Press 2015-09-02 /pmc/articles/PMC4562756/ /pubmed/26366096 http://dx.doi.org/10.2147/OTT.S88528 Text en © 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Wang, Rong-jiang
Tang, Jian-er
Chen, Yu
Gao, Jian-guo
Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title_full Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title_fullStr Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title_full_unstemmed Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title_short Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
title_sort dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562756/
https://www.ncbi.nlm.nih.gov/pubmed/26366096
http://dx.doi.org/10.2147/OTT.S88528
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