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Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer
BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562756/ https://www.ncbi.nlm.nih.gov/pubmed/26366096 http://dx.doi.org/10.2147/OTT.S88528 |
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author | Wang, Rong-jiang Tang, Jian-er Chen, Yu Gao, Jian-guo |
author_facet | Wang, Rong-jiang Tang, Jian-er Chen, Yu Gao, Jian-guo |
author_sort | Wang, Rong-jiang |
collection | PubMed |
description | BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search of PubMed database and EMBASE database up to April 2015. A random effects model was used to calculate the summary relative risks (RRs) and their corresponding 95% confidence intervals (CIs). RESULTS: Twenty-seven epidemiological studies (18 case–control studies and nine cohort studies) were included in the final analysis. The pooled RRs of prostate cancer were 0.94 (95% CI 0.85–1.05, P=0.285), 1.13 (95% CI 0.98–1.30, P=0.095), 0.96 (95% CI 0.81–1.14, P=0.672), 1.06 (95% CI 0.96–1.18, P=0.254), and 1.04 (95% CI 0.91–1.18, P=0.590) for dietary fiber, whole grains, carbohydrate, GI, and GL, respectively. There was no evidence of significant publication bias based on the Begg’s test and Egger’s test. CONCLUSION: The findings of this meta-analysis indicate that, based on available information, dietary fiber, whole grains, carbohydrate, GI, and GL are not associated with the risk of prostate cancer. |
format | Online Article Text |
id | pubmed-4562756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-45627562015-09-11 Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer Wang, Rong-jiang Tang, Jian-er Chen, Yu Gao, Jian-guo Onco Targets Ther Original Research BACKGROUND: The relationships between dietary fiber, whole grains, carbohydrate, glycemic index (GI), glycemic load (GL), and prostate cancer risk are unclear. We conducted a systematic review and meta-analysis to investigate these associations. METHODS: Relevant studies were identified by a search of PubMed database and EMBASE database up to April 2015. A random effects model was used to calculate the summary relative risks (RRs) and their corresponding 95% confidence intervals (CIs). RESULTS: Twenty-seven epidemiological studies (18 case–control studies and nine cohort studies) were included in the final analysis. The pooled RRs of prostate cancer were 0.94 (95% CI 0.85–1.05, P=0.285), 1.13 (95% CI 0.98–1.30, P=0.095), 0.96 (95% CI 0.81–1.14, P=0.672), 1.06 (95% CI 0.96–1.18, P=0.254), and 1.04 (95% CI 0.91–1.18, P=0.590) for dietary fiber, whole grains, carbohydrate, GI, and GL, respectively. There was no evidence of significant publication bias based on the Begg’s test and Egger’s test. CONCLUSION: The findings of this meta-analysis indicate that, based on available information, dietary fiber, whole grains, carbohydrate, GI, and GL are not associated with the risk of prostate cancer. Dove Medical Press 2015-09-02 /pmc/articles/PMC4562756/ /pubmed/26366096 http://dx.doi.org/10.2147/OTT.S88528 Text en © 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Wang, Rong-jiang Tang, Jian-er Chen, Yu Gao, Jian-guo Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title | Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title_full | Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title_fullStr | Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title_full_unstemmed | Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title_short | Dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
title_sort | dietary fiber, whole grains, carbohydrate, glycemic index, and glycemic load in relation to risk of prostate cancer |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562756/ https://www.ncbi.nlm.nih.gov/pubmed/26366096 http://dx.doi.org/10.2147/OTT.S88528 |
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