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A Proton Pump Inhibitor’s Effect on Bone Metabolism Mediated by Osteoclast Action in Old Age: A Prospective Randomized Study

BACKGROUND/AIMS: Proton pump inhibitors (PPIs) act by irreversibly binding to the H(+)-K(+)-ATPase of the proton pump in parietal cells and may possibly affect the vacuolar H(+)-ATPase in osteoclasts. METHODS: We investigated the effect of 8 weeks of PPI treatment on the parameters of bone turnover...

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Detalles Bibliográficos
Autores principales: Jo, Yunju, Park, Eunkyoung, Ahn, Sang Bong, Jo, Young Kwan, Son, Byungkwan, Kim, Seong Hwan, Park, Young Sook, Kim, Hyo Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gut and Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562777/
https://www.ncbi.nlm.nih.gov/pubmed/25473078
http://dx.doi.org/10.5009/gnl14135