Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predicts Poor Survival of Breast Carcinoma Patients()

BACKGROUND: Poly(ADP-ribose) polymerase 1 (PARP1), γH2AX, BRCA1, and BRCA2 are conventional molecular indicators of DNA damage in cells and are often overexpressed in various cancers. In this study, we aimed, using immunohistochemical detection, whether the co-expression of PARP1, γH2AX, BRCA1, and...

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Detalles Bibliográficos
Autores principales: Park, See-Hyoung, Noh, Sang Jae, Kim, Kyoung Min, Bae, Jun Sang, Kwon, Keun Sang, Jung, Sung Hoo, Kim, Jung Ryul, Lee, Ho, Chung, Myoung Ja, Moon, Woo Sung, Kang, Myoung Jae, Jang, Kyu Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562981/
https://www.ncbi.nlm.nih.gov/pubmed/26310369
http://dx.doi.org/10.1016/j.tranon.2015.04.004

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