Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren's Syndrome Immunopathogenesis

The activated NF-κB signaling pathway plays an important role in pathogenesis of primary Sjögren's syndrome (pSS). The inhibitor of κB (IκB) kinase (IKK) family such as IKKα, IKKβ, IKKγ, and IKKε, is required for this signaling. Our aim was to investigate the role of IKKα/β/γ/ε in patients with...

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Detalles Bibliográficos
Autores principales: Chen, Weiqian, Lin, Jin, Cao, Heng, Xu, Danyi, Xu, Bei, Xu, Liqin, Yue, Lihuan, Sun, Chuanyin, Wu, Guolin, Qian, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563092/
https://www.ncbi.nlm.nih.gov/pubmed/26380323
http://dx.doi.org/10.1155/2015/534648

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