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Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors

OBJECTIVE: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. METHODS: Hp infection status was determined by using Urea Breath Test (UBT). P...

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Autores principales: Çınar, Alev, Sadıç, Murat, İkbal Atılgan, Hasan, Baskın, Aylin, Koca, Gökhan, Demirel, Koray, Korkmaz, Meliha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563172/
https://www.ncbi.nlm.nih.gov/pubmed/26316471
http://dx.doi.org/10.4274/mirt.53215
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author Çınar, Alev
Sadıç, Murat
İkbal Atılgan, Hasan
Baskın, Aylin
Koca, Gökhan
Demirel, Koray
Korkmaz, Meliha
author_facet Çınar, Alev
Sadıç, Murat
İkbal Atılgan, Hasan
Baskın, Aylin
Koca, Gökhan
Demirel, Koray
Korkmaz, Meliha
author_sort Çınar, Alev
collection PubMed
description OBJECTIVE: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. METHODS: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). RESULTS: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. CONCLUSION: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family.
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spelling pubmed-45631722015-12-18 Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors Çınar, Alev Sadıç, Murat İkbal Atılgan, Hasan Baskın, Aylin Koca, Gökhan Demirel, Koray Korkmaz, Meliha Mol Imaging Radionucl Ther Original Article OBJECTIVE: To investigate the prevalence of Helicobacter pylori (Hp) infection in pre-school and school age children with C-14 urea breath test, and to explore its association with age and socioeconomic factors in Turkey. METHODS: Hp infection status was determined by using Urea Breath Test (UBT). Patients who had previous gastric surgery, Hp eradication treatment or equivocal UBT results were excluded. A questionnaire was administered to elicit information on gender, age, ABO/Rh blood group type, presence of gastric disease in the family, domestic animal in the household, and treatment for idiopathic Iron Deficiency Anemia (IDA). RESULTS: This retrospective study included 500 pediatric patients (179 boys, 321 girls, mean age 10.7±4.3 years) of whom 62 (12.4%) were aged ≤6 years and 438 (87.6%) were aged 7 to 16 years. Helicobacter pylori (Hp) was positive in 245 (49%) cases. In the pre-school age group, 21/62 cases (34%) had positive UBT while in the school age group 224/438 children (51%) had positive UBT. A family history of dyspepsia and pet ownership were not associated with Hp positivity. Hp positive 76 (29.8%) children were on IDA treatment but this was not statistically significant. CONCLUSION: The Hp infection positivity rate was 49% in the pediatric age study group. The positivity rate was significantly lower at preschool age than school age, and it increased with age. There was no association with gender, ABO/Rh blood groups, presence of domestic pets, IDA, or history of gastric disease in the family. Galenos Publishing 2015-06 2015-06-17 /pmc/articles/PMC4563172/ /pubmed/26316471 http://dx.doi.org/10.4274/mirt.53215 Text en © Molecular Imaging and Radionuclide Therapy, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Çınar, Alev
Sadıç, Murat
İkbal Atılgan, Hasan
Baskın, Aylin
Koca, Gökhan
Demirel, Koray
Korkmaz, Meliha
Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title_full Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title_fullStr Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title_full_unstemmed Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title_short Prevalence of Helicobacter Pylori Infection in School and Pre-School Aged Children with C-14 Urea Breath Test and the Association with Familial and Environmental Factors
title_sort prevalence of helicobacter pylori infection in school and pre-school aged children with c-14 urea breath test and the association with familial and environmental factors
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563172/
https://www.ncbi.nlm.nih.gov/pubmed/26316471
http://dx.doi.org/10.4274/mirt.53215
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