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Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer
Stemness was recently depicted as a dynamic condition in normal and tumor cells. We found that the embryonic protein Cripto-1 (CR1) was expressed by normal stem cells at the bottom of colonic crypts and by cancer stem cells (CSCs) in colorectal tumor tissues. CR1-positive populations isolated from p...
Autores principales: | Francescangeli, F, Contavalli, P, De Angelis, M L, Baiocchi, M, Gambara, G, Pagliuca, A, Fiorenzano, A, Prezioso, C, Boe, A, Todaro, M, Stassi, G, Castro, N P, Watanabe, K, Salomon, D S, De Maria, R, Minchiotti, G, Zeuner, A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563784/ https://www.ncbi.nlm.nih.gov/pubmed/26343543 http://dx.doi.org/10.1038/cdd.2015.19 |
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