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DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose

Macroautophagy is a membrane-trafficking process that delivers cytoplasmic constituents to lysosomes for degradation. The process operates under basal conditions as a mechanism to turnover damaged or misfolded proteins and organelles. As a result, it has a major role in preserving cellular integrity...

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Detalles Bibliográficos
Autores principales: Mrschtik, M, O'Prey, J, Lao, L Y, Long, J S, Beaumatin, F, Strachan, D, O'Prey, M, Skommer, J, Ryan, K M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563785/
https://www.ncbi.nlm.nih.gov/pubmed/25929859
http://dx.doi.org/10.1038/cdd.2015.26