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Deoxyinosine repair in nuclear extracts of human cells

BACKGROUND: Deamination of adenine can occur spontaneously under physiological conditions generating the highly mutagenic lesion, hypoxanthine. This process is enhanced by ROS from exposure of DNA to ionizing radiation, UV light, nitrous acid, or heat. Hypoxanthine in DNA can pair with cytosine whic...

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Detalles Bibliográficos
Autores principales:	Lee, Chia-Chia, Yang, Ya-Chien, Goodman, Steven D., Chen, Shi, Huang, Teng-Yung, Cheng, Wern-Cherng, Lin, Liang-In, Fang, Woei-horng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563847/ https://www.ncbi.nlm.nih.gov/pubmed/26357532 http://dx.doi.org/10.1186/s13578-015-0044-8

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