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Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia

BACKGROUND AND AIMS: Caudal-epidural, the most commonly used regional analgesia technique, is virtually free of measurable hemodynamic effects, thus adding a new dimension to the evolving necessity of pediatric postoperative pain management. Though, bupivacaine is the most commonly used drug for thi...

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Autores principales: Sengupta, Swapnadeep, Mukherji, Sudakshina, Sheet, Jagabandhu, Mandal, Anamitra, Swaika, Sarbari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563976/
https://www.ncbi.nlm.nih.gov/pubmed/26417128
http://dx.doi.org/10.4103/0259-1162.154541
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author Sengupta, Swapnadeep
Mukherji, Sudakshina
Sheet, Jagabandhu
Mandal, Anamitra
Swaika, Sarbari
author_facet Sengupta, Swapnadeep
Mukherji, Sudakshina
Sheet, Jagabandhu
Mandal, Anamitra
Swaika, Sarbari
author_sort Sengupta, Swapnadeep
collection PubMed
description BACKGROUND AND AIMS: Caudal-epidural, the most commonly used regional analgesia technique, is virtually free of measurable hemodynamic effects, thus adding a new dimension to the evolving necessity of pediatric postoperative pain management. Though, bupivacaine is the most commonly used drug for this purpose, ropivacaine has emerged as a safer alternative, with the addition of opioids, like fentanyl, increasing the effective duration of analgesia. With this overview, our present study was designed to compare the postoperative analgesic efficacy of bupivacaine-fentanyl and ropivacaine-fentanyl combinations by caudal-epidural technique in pediatric infraumbilical surgeries. MATERIALS AND METHODS: Totally, 60 pediatric patients, of either sex, aged between 2 and 8 years, American Society of Anesthesiologists physical status I and II, undergoing elective infraumbilical surgeries were assigned into two groups, Group BF receiving bupivacaine 0.25%, 0.7 ml/kg and Group RF receiving ropivacaine 0.25%, 0.7 ml/kg with fentanyl 1 μg/kg added to each group. Assessment of pain was done using “Hannallah pain scale.” Consumption of the total amount of rescue analgesic and time to requirement of the first dose, as also duration of motor blockade were noted. Perioperative hemodynamics and any adverse effects were monitored at regular intervals. RESULTS: The RF Group experienced significantly longer duration of effective postoperative analgesia, with significantly shorter duration of motor blockade and lesser total analgesic requirement in comparison to the BF Group. Hemodynamically, patients in both the groups, were equally stable. CONCLUSION: Ropivacaine, with an equipotent analgesic efficacy and a lesser duration of motor block, can be used as an alternative to bupivacaine for pediatric postoperative pain care through the caudal route.
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spelling pubmed-45639762015-09-28 Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia Sengupta, Swapnadeep Mukherji, Sudakshina Sheet, Jagabandhu Mandal, Anamitra Swaika, Sarbari Anesth Essays Res Original Article BACKGROUND AND AIMS: Caudal-epidural, the most commonly used regional analgesia technique, is virtually free of measurable hemodynamic effects, thus adding a new dimension to the evolving necessity of pediatric postoperative pain management. Though, bupivacaine is the most commonly used drug for this purpose, ropivacaine has emerged as a safer alternative, with the addition of opioids, like fentanyl, increasing the effective duration of analgesia. With this overview, our present study was designed to compare the postoperative analgesic efficacy of bupivacaine-fentanyl and ropivacaine-fentanyl combinations by caudal-epidural technique in pediatric infraumbilical surgeries. MATERIALS AND METHODS: Totally, 60 pediatric patients, of either sex, aged between 2 and 8 years, American Society of Anesthesiologists physical status I and II, undergoing elective infraumbilical surgeries were assigned into two groups, Group BF receiving bupivacaine 0.25%, 0.7 ml/kg and Group RF receiving ropivacaine 0.25%, 0.7 ml/kg with fentanyl 1 μg/kg added to each group. Assessment of pain was done using “Hannallah pain scale.” Consumption of the total amount of rescue analgesic and time to requirement of the first dose, as also duration of motor blockade were noted. Perioperative hemodynamics and any adverse effects were monitored at regular intervals. RESULTS: The RF Group experienced significantly longer duration of effective postoperative analgesia, with significantly shorter duration of motor blockade and lesser total analgesic requirement in comparison to the BF Group. Hemodynamically, patients in both the groups, were equally stable. CONCLUSION: Ropivacaine, with an equipotent analgesic efficacy and a lesser duration of motor block, can be used as an alternative to bupivacaine for pediatric postoperative pain care through the caudal route. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4563976/ /pubmed/26417128 http://dx.doi.org/10.4103/0259-1162.154541 Text en Copyright: © Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sengupta, Swapnadeep
Mukherji, Sudakshina
Sheet, Jagabandhu
Mandal, Anamitra
Swaika, Sarbari
Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title_full Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title_fullStr Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title_full_unstemmed Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title_short Caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
title_sort caudal-epidural bupivacaine versus ropivacaine with fentanyl for paediatric postoperative analgesia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563976/
https://www.ncbi.nlm.nih.gov/pubmed/26417128
http://dx.doi.org/10.4103/0259-1162.154541
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