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Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts
Hypertrophic scarring/hypertrophic scars (HS) is a highly prevalent condition following burns and trauma wounds. Numerous studies have demonstrated that transforming growth factor-β1 (TGF-β1) plays an essential role in the wound healing process by regulating cell differentiation, collagen production...
Autores principales: | FAN, CHEN, DONG, YING, XIE, YAN, SU, YONGHUA, ZHANG, XUFANG, LEAVESLEY, DAVID, UPTON, ZEE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564088/ https://www.ncbi.nlm.nih.gov/pubmed/26239419 http://dx.doi.org/10.3892/ijmm.2015.2299 |
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