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Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) are key events in the development of artery restenosis following percutaneous coronary intervention. Digoxin has long been used in the treatment of heart failure and has been shown to inhibit the proliferation of cance...

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Detalles Bibliográficos
Autores principales: YAN, GAOLIANG, WANG, QINGJIE, HU, SHENGDA, WANG, DONG, QIAO, YONG, MA, GENSHAN, TANG, CHENGCHUN, GU, YUCHUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564091/
https://www.ncbi.nlm.nih.gov/pubmed/26311435
http://dx.doi.org/10.3892/ijmm.2015.2320