Cargando…

Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury

The increased proliferation and migration of vascular smooth muscle cells (VSMCs) are key events in the development of artery restenosis following percutaneous coronary intervention. Digoxin has long been used in the treatment of heart failure and has been shown to inhibit the proliferation of cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	YAN, GAOLIANG, WANG, QINGJIE, HU, SHENGDA, WANG, DONG, QIAO, YONG, MA, GENSHAN, TANG, CHENGCHUN, GU, YUCHUN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564091/ https://www.ncbi.nlm.nih.gov/pubmed/26311435 http://dx.doi.org/10.3892/ijmm.2015.2320

Ejemplares similares

Activation of Inward Rectifier K(+) Channel 2.1 by PDGF-BB in Rat Vascular Smooth Muscle Cells through Protein Kinase A
por: Tang, Chengchun, et al.
Publicado: (2020)

Regulation of Rat Intrapulmonary Arterial Tone by Arachidonic Acid and Prostaglandin E2 during Hypoxia
por: Yan, Gaoliang, et al.
Publicado: (2013)

A novel PDGF receptor inhibitor-eluting stent attenuates in-stent neointima formation in a rabbit carotid model
por: Huang, Chen, et al.
Publicado: (2017)

Inhibition of p90RSK Ameliorates PDGF-BB-Mediated Phenotypic Change of Vascular Smooth Muscle Cell and Subsequent Hyperplasia of Neointima
por: Hwang, Ae-Rang, et al.
Publicado: (2023)

PTBP1 Targets ILK to Regulate the Hypoxia-Induced Phenotypic Transformation of Pulmonary Artery Smooth Muscle Cells
por: Yan, Gaoliang, et al.
Publicado: (2021)

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly
Publicado: (1992)

Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade
por: Lu, Qing-Bo, et al.
Publicado: (2017)

RhoGDI1-Cdc42 Signaling Is Required for PDGF-BB-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Neointima Formation
por: Qi, Yan, et al.
Publicado: (2021)

Low plasma PDGF-BB levels are associated with estradiol in postmenopausal osteoporosis: PDGF-BB mediated by estradiol in women
por: Tang, Lanhua, et al.
Publicado: (2017)

The Predictive Value of Myeloperoxidase for Contrast-Induced Nephropathy After Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction
por: Yan, Gaoliang, et al.
Publicado: (2021)

The Association of Serum Lactate Level with the Occurrence of Contrast-Induced Acute Kidney Injury and Long-Term Prognosis in Patients Undergoing Emergency Percutaneous Coronary Intervention
por: Yan, Gaoliang, et al.
Publicado: (2021)

Different levels of glycosylated hemoglobin influence severity and long-term prognosis of coronary heart disease patients with stent implantation
por: WANG, JING, et al.
Publicado: (2015)

A fibronectin peptide redirects PDGF-BB/PDGFR complexes to macropinocytosis-like internalization and augments PDGF-BB survival signals
por: Zhu, Jia, et al.
Publicado: (2013)

The Predictive Value of Soluble Urokinase-Type Plasminogen Activator Receptor in Contrast-Induced Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Intervention
por: Qin, Yuhan, et al.
Publicado: (2021)

Osteoclasts Control Osteoblast Chemotaxis via PDGF-BB/PDGF Receptor Beta Signaling
por: Sanchez-Fernandez, Maria Arantzazu, et al.
Publicado: (2008)

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors
Publicado: (1994)

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis
por: Wang, Xingqi, et al.
Publicado: (2016)

A Promising Candidate in Tendon Healing Events—PDGF-BB
por: Chen, Yixuan, et al.
Publicado: (2022)

Evodiamine Attenuates PDGF-BB-Induced Migration of Rat Vascular Smooth Muscle Cells through Activating PPARγ
por: Ge, Xie, et al.
Publicado: (2015)

The chemotactic response to PDGF-BB: evidence of a role for Ras
Publicado: (1995)

Lateral Flow Aptasensor for Simultaneous Detection of Platelet-Derived Growth Factor-BB (PDGF-BB) and Thrombin
por: Liu, Guodong, et al.
Publicado: (2019)

Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts
por: Kainuma, Shingo, et al.
Publicado: (2017)

PDGF-BB serum levels are decreased in adult onset Pompe patients
por: Fernández-Simón, Esther, et al.
Publicado: (2019)

Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in mice
por: Chen, Lei, et al.
Publicado: (2021)

PDGF-BB-derived supramolecular hydrogel for promoting skin wound healing
por: Jian, Ke, et al.
Publicado: (2022)

Bone-derived PDGF-BB drives brain vascular calcification in male mice
por: Wang, Jiekang, et al.
Publicado: (2023)

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB
por: Gao, Si-yong, et al.
Publicado: (2017)

Preoperative Serum Levels of PDGF-AB, PDGF-BB, TGF-α, EGF and ANG-2 in the Diagnosis of Endometrial Cancer
por: Kozłowski, Mateusz, et al.
Publicado: (2023)

Serial measurements of serum PDGF-AA, PDGF-BB, FGF2, and VEGF in multiresistant ovarian cancer patients treated with bevacizumab
por: Madsen, Christine Vestergaard, et al.
Publicado: (2012)

Oral Charcoal Adsorbents Attenuate Neointima Formation of Arteriovenous Fistulas
por: Shih, Yu-Chung, et al.
Publicado: (2020)

PDGF-BB Does Not Accelerate Healing in Diabetic Mice with Splinted Skin Wounds
por: Park, Shin Ae, et al.
Publicado: (2014)

Role of TG2-Mediated SERCA2 Serotonylation on Hypoxic Pulmonary Vein Remodeling
por: Liu, Bo, et al.
Publicado: (2020)

Down‐regulation of Suv39h1 attenuates neointima formation after carotid artery injury in diabetic rats
por: Zhang, Jing, et al.
Publicado: (2019)

PPARγ Inhibits VSMC Proliferation and Migration via Attenuating Oxidative Stress through Upregulating UCP2
por: Zhou, Yi, et al.
Publicado: (2016)

Endostatin attenuates PDGF-BB- or TGF-β1-induced HSCs activation via suppressing RhoA/ROCK1 signal pathways
por: Ren, Haitao, et al.
Publicado: (2019)

Effect on Osteogenic Differentiation of Genetically Modified IL4 or PDGF-BB Over-Expressing and IL4-PDGF-BB Co-Over-Expressing Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro
por: Tsubosaka, Masanori, et al.
Publicado: (2021)

PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates Osteogenesis in a Temporal Manner
por: Wang, Fangqian, et al.
Publicado: (2023)

Activation of AMPK by Telmisartan Decreases Basal and PDGF-stimulated VSMC Proliferation via Inhibiting the mTOR/p70S6K Signaling Axis
por: Hwang, Yun-Jin, et al.
Publicado: (2020)

Fibronectin peptides that bind PDGF-BB enhance survival of cells and tissue under stress
por: Lin, Fubao, et al.
Publicado: (2013)

Predictive Value of Diminished Serum PDGF-BB after Curative Resection of Hepatocellular Cancer
por: Aryal, Bibek, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p681cfc3hunvpbv7hve0p3vjgh