Cargando…
Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a
Drug resistance remains a major challenge in cancer therapy. Butein, a polyphenolic compound, has been shown to exhibit anticancer activity through the inhibition of the activation of the protein kinase B (PKB/AKT) and mitogen-activated protein kinase (MAPK) pathways, which are two pathways known to...
Autores principales: | ZHANG, LIRUI, YANG, XIAOFENG, LI, XU, LI, CHEN, ZHAO, LE, ZHOU, YUANYUAN, HOU, HUILIAN |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564095/ https://www.ncbi.nlm.nih.gov/pubmed/26310353 http://dx.doi.org/10.3892/ijmm.2015.2324 |
Ejemplares similares
-
Silibinin Alleviates Muscle Atrophy Caused by Oxidative Stress Induced by Cisplatin through ERK/FoxO and JNK/FoxO Pathways
por: Chi, Meng-yi, et al.
Publicado: (2022) -
Knockdown of RNF6 inhibits HeLa cervical cancer cell growth via suppression of MAPK/ERK signaling
por: Zhu, Kang, et al.
Publicado: (2021) -
Synergistic Enhancement of Cisplatin Cytotoxicity by SN‐38, an Active Metabolite of CPT‐11, for Cisplatin‐resistant HeLa Cells
por: Minagawa, Yukihisa, et al.
Publicado: (1994) -
A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells
por: Galli, Soledad, et al.
Publicado: (2009) -
Knockdown of Wip1 Enhances Sensitivity to Radiation in HeLa Cells Through Activation of p38 MAPK
por: Wang, Hong-yong, et al.
Publicado: (2015)