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Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a

Drug resistance remains a major challenge in cancer therapy. Butein, a polyphenolic compound, has been shown to exhibit anticancer activity through the inhibition of the activation of the protein kinase B (PKB/AKT) and mitogen-activated protein kinase (MAPK) pathways, which are two pathways known to...

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Detalles Bibliográficos
Autores principales: ZHANG, LIRUI, YANG, XIAOFENG, LI, XU, LI, CHEN, ZHAO, LE, ZHOU, YUANYUAN, HOU, HUILIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564095/
https://www.ncbi.nlm.nih.gov/pubmed/26310353
http://dx.doi.org/10.3892/ijmm.2015.2324

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